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Fundamentals of Molecular Evolution, by Dan Graur, Wen-Hsiung Li
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This book describes the dynamics of evolutionary change at the molecular level, the driving forces behind the evolutionary process, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology involved in dealing with molecular data from an evolutionary perspective, and the logic of molecular hypothesis testing. The Second Edition incorporates newly acquired evolutionary insight from genome projects involving bacteria, plants, and animals, as well as analytical tools that have been developed and perfected in the last decade, and has been brought up to date in line with the many advances in genomics, protein engineering, computational biology, and bioinformatics.
The authors explain evolutionary phenomena at the molecular level in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Both mathematical and intuitive explanations are provided, and examples that support and clarify the many theoretical arguments and methodological discussions are included.
- Sales Rank: #664680 in Books
- Brand: Brand: Sinauer Associates
- Published on: 2000-01-15
- Ingredients: Example Ingredients
- Original language: English
- Number of items: 1
- Dimensions: 9.25" h x 7.50" w x 1.00" l, 1.80 pounds
- Binding: Paperback
- 481 pages
- Used Book in Good Condition
Review
The 'Fundamentals' can serve both as an excellent text book for students of different biological disciplines and as a very useful introduction into molecular evolution for professional readers. ... Undoubtedly, this book should be an essential purchase for all libraries in higher education institutions with biology departments." --V. N. Ksenzenko and Y. A. Trotsenko, Journal of Chemical Technology and Biotechnology
About the Author
DAN GRAUR, Tel Aviv University WEN-HSIUNG LI, University of Chicago
Most helpful customer reviews
32 of 34 people found the following review helpful.
In depth, informative
By A Customer
This is a very complex, indepth, informative book on molecular and genetic evolution. Explainations of genetic drift, mutation rates, times to fixation, patterns in evolutionary changes. Lots of statistical information on how allele frequencies change. Written for a knowledgable audiance with a good understanding of evolution and genetics. Gives informative understanding of trends in evolution beyond natural selection. Supports neutral theory of evolution quite strongly.
2 of 2 people found the following review helpful.
An excellent introduction or review of molecular evolutionary principles.
By phylo_phd
I have been using this book as a study guide for my qualifying examinations in evolutionary biology & genetics. It is concise and well-illustrated. The citations to original papers are exceptional. The authors do an amazing job of making difficult material seem simple. I'm now considering using this book as the basis for a lecture course. Maybe for those who enjoy crunching equations for hours this is not the best text, but for everyone else who wants practical knowledge that is readily applicable to phylogenetic and bioinformatic research in the field of molecular evolution--I have seen no better text.
8 of 11 people found the following review helpful.
Containing some obvious errors
By KY
The book contains some obvious errors. For example, when describing dynamic programming, the recursive formula is wrong. Another example is on P.162, where it is said that the KA/KS ratio exceeds 100 for conservative genes.
In general, the book briefly touches on a lot of topics. While the book is meant to serve an introductory purpose, some details necessary for understanding the concepts are missing.
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